Anti-ACE1 Rabbit pAb
- 100ug (NP20470) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC,FC
Purify method:Affinity Chromatography
Species:Human,Mouse
Gene Name:
Synonyms:Angiotensin-converting enzyme; somatic isoform precursor; CD143 antigen; DCP; DCP1; Dipeptidyl carboxypeptidase I; Kininase II;
Gene Synonyms:
Gene Full Name:
Gene Infomation:Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releas
Antigen:A synthesized peptide derived from human ACE1
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:ACE1 Antibody detects endogenous levels of total ACE1
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB 1:500~1:1000 IHC 1:50~1:200 FC 1:30
Mole Mass:195kDa
Location:Cytoplasm;
Concentration:
Sequence Similarity:Belongs to the peptidase M2 family.
Gene Id:
SwissProt ID:P12821
Unigene:
Nucleotide Accession:
Tissue specificity:ACE1 Antibody detects endogenous levels of total ACE1
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Background:Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.