Anti-ACTL6A (N-term) Rabbit pAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:Rabbit Ig
Host:Rabbit
Application:WB
Purify method:Affinity purified
Species:Human
Gene Name:actl6a
Synonyms:Actin-like protein 6A, 53 kDa BRG1-associated factor A, Actin-related protein Baf53a, ArpNbeta, BRG1-associated factor 53A, BAF53A, INO80 complex subunit K, ACTL6A, BAF53, BAF53A, INO80K
Gene Synonyms:
Gene Full Name:
Gene Infomation:This gene encodes a family member of actin-relatedproteins (ARPs), which share significant amino acid sequenceidentity to conventional actins. Both actins and ARPs have an actinfold, which is an ATP-binding cleft, as a common feature. The ARPsare involved in diverse cellular processes, including vesiculartransport, spindle orientation, nuclear migration and chromatinremodeling. This gene encodes a 53 kDa subunit protein of the BAF(BRG1/brm-associated factor) complex in mammals, which isfunctionally related to SWI/SNF complex in S. cerevisiae andDrosophila; the latter is thought to facilitate transcriptionalactivation of specific genes by antagonizing chromatin-mediatedtranscriptional repression. Together with beta-actin, it isrequired for maximal ATPase activity of BRG1, and for theassociation of the BAF complex with chromatin/matrix. Threetranscript variants that encode two different protein isoforms havebeen described.
Antigen:This ACTL6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human ACTL6A.
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:RB36747
Dilution:WB::1:1000
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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.