Anti-ANPEP/CD13 Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG2a

Host:Mouse

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:anpep/cd13

Synonyms:Aminopeptidase N, AP-N, hAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, gp150, CD13, ANPEP, APN, CD13, PEPN

Gene Synonyms:

Gene Full Name:

Gene Infomation:Aminopeptidase N is located in the small-intestinal andrenal microvillar membrane, and also in other plasma membranes. Inthe small intestine aminopeptidase N plays a role in the finaldigestion of peptides generated from hydrolysis of proteins bygastric and pancreatic proteases. Its function in proximal tubularepithelial cells and other cell types is less clear. The largeextracellular carboxyterminal domain contains a pentapeptideconsensus sequence characteristic of members of the zinc-bindingmetalloproteinase superfamily. Sequence comparisons with knownenzymes of this class showed that CD13 and aminopeptidase N areidentical. The latter enzyme was thought to be involved in themetabolism of regulatory peptides by diverse cell types, includingsmall intestinal and renal tubular epithelial cells, macrophages,granulocytes, and synaptic membranes from the CNS. Humanaminopeptidase N is a receptor for one strain of human coronavirusthat is an important cause of upper respiratory tract infections.Defects in this gene appear to be a cause of various types ofleukemia or lymphoma.

Antigen:This ANPEP/CD13 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from human ANPEP/CD13.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:505CT12.1.2

Dilution:WB::1:100~250

Mole Mass:

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Sequence Similarity:

Gene Id:

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Unigene:

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Tissue specificity:

Storage:

Buffer condition:Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.