Anti-APOBEC3A (N-term) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:

Synonyms:DNA dC->dU-editing enzyme APOBEC-3A, A3A, 354-, Phorbolin-1, APOBEC3A

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene is a member of the cytidine deaminase genefamily. It is one of seven related genes or pseudogenes found in acluster, thought to result from gene duplication, on chromosome 22.Members of the cluster encode proteins that are structurally andfunctionally related to the C to U RNA-editing cytidine deaminaseAPOBEC1. The protein encoded by this gene lacks the zinc bindingactivity of other family members. The protein plays a role inimmunity, by restricting transmission of foreign DNA such asviruses. One mechanism of foreign DNA restriction is deamination offoreign double-stranded DNA cytidines to uridines, which leads toDNA degradation. However, other mechanisms are also thought to beinvolved, as anti-viral effect is not dependent on deaminaseactivity. One allele of this gene results from the deletion ofapproximately 29.5 kb of sequence between this gene, APOBEC3A, andthe adjacent gene APOBEC3B. The breakpoints of the deletion arewithin the two genes, so the deletion allele is predicted to havethe promoter and coding region of APOBEC3A, but the 3' UTR ofAPOBEC3B.

Antigen:This APOBEC3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human APOBEC3A.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::1:1000

Mole Mass:

Location:

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Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

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Tissue specificity:

Storage:

Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.