Anti-ARRB1 Mouse mAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:IgG1
Host:Mouse
Application:WB
Purify method:Unpurification
Species:Human
Gene Name:arrb1
Synonyms:ARB1; ARR1
Gene Synonyms:ARB1; ARR1
Gene Full Name:
Gene Infomation:Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
Antigen:Purified recombinant fragment of human ARRB1 (AA: 89-268) expressed in E. Coli.
Antigen Synonyms:
Clonality:Monclonal antibody
Source:
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:4E11B1
Dilution:
Mole Mass:47
Location:
Concentration:
Sequence Similarity:
Gene Id:408
SwissProt ID:
Unigene:
Nucleotide Accession:
Tissue specificity:
Storage:
Buffer condition:Purified antibody in PBS with 0.05% sodium azide.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.