Anti-Akt2 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human,Mouse,Monkey

Gene Name:akt2

Synonyms:AKT 2;AKT 2;Akt2;AKT2_HUMAN;HIHGHH;murine thymoma viral (v-akt) homolog-2;PKB;PKB;PKB beta;PKB beta;PKBB;PKBBETA;PRKBB;PRKBB;Protein kinase Akt 2;Protein kinase Akt-2;Protein kinase B beta;RAC BETA;RAC beta serine threonine protein kinase;RAC PK beta;Rac protein kinase beta;Rac protein kinase beta;RAC-BETA;RAC-beta serine/threonine-protein kinase; RAC-PK-beta;V AKT Murine Thymoma Viral Oncogene Homolog 2.

Gene Synonyms:PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA

Gene Full Name:

Gene Infomation:This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]

Antigen:Peptide sequence around aa. 472~476 (Q-F-S-Y-S) derived from human AKT2.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::1:2000

Mole Mass:60

Location:Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Note: Localizes within both nucleus and cytoplasm of proliferative primary myoblasts and mostly within the nucleus of differentiated primary myoblasts. By virtue of the N-terminal PH domain,

Concentration:1mg/ml

Sequence Similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. Contains 1 AGC-kinase C-terminal domain. Contains 1 PH domain. Contains 1 protein kinase domain.

Gene Id:208

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:The antibody detects endogenous level of total AKT2 protein.

Storage:

Buffer condition:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.