Anti-Amyloid-β Rabbit pAb
- 100ug (NP22473) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:IgG
Host:Rabbit
Application:WB
Purify method:Affinity purified
Species:Human,Mouse,Rat
Gene Name:APP
Synonyms:amyloid beta (A4) precursor protein
Gene Synonyms:AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
Gene Full Name:
Gene Infomation:This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
Antigen:Synthesized peptide derived from Amyloid-β at AA range: 221-270
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB::1:500-2000IHC::1:50-300
Mole Mass:87
Location:Membrane > Clathrin-coated pit;
Concentration:
Sequence Similarity:Contains 1 BPTI/Kunitz inhibitor domain.
Gene Id:351
SwissProt ID:
Unigene:
Nucleotide Accession:
Tissue specificity:Amyloid-β Polyclonal Antibody detects endogenous levels of Amyloid-β
Storage:
Buffer condition:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.