Anti-BAX Mouse mAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:IgG2b
Host:Mouse
Application:WB
Purify method:Affinity purified
Species:Human
Gene Name:bax
Synonyms:Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX, BCL2L4
Gene Synonyms:
Gene Full Name:
Gene Infomation:The protein encoded by this gene belongs to the BCL2protein family. BCL2 family members form hetero- or homodimers andact as anti- or pro-apoptotic regulators that are involved in awide variety of cellular activities. This protein forms aheterodimer with BCL2, and functions as an apoptotic activator.This protein is reported to interact with, and increase the openingof, the mitochondrial voltage-dependent anion channel (VDAC), whichleads to the loss in membrane potential and the release ofcytochrome c. The expression of this gene is regulated by the tumorsuppressor P53 and has been shown to be involved in P53-mediatedapoptosis. Multiple alternatively spliced transcript variants,which encode different isoforms, have been reported for this gene.
Antigen:This BAXantibody is generated from mice immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from human BAX .
Antigen Synonyms:
Clonality:Monclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:557CT5.2.1
Dilution:WB::1:100
Mole Mass:
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Sequence Similarity:
Gene Id:
SwissProt ID:
Unigene:
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Tissue specificity:
Storage:
Buffer condition:Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.