Anti-BMPR1B (Center) Rabbit pAb
- 100ug (NP30716) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:Rabbit Ig
Host:Rabbit
Application:WB,IHC-P
Purify method:Affinity purified
Species:Human
Gene Name:bmpr1b
Synonyms:Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, CDw293, BMPR1B
Gene Synonyms:
Gene Full Name:
Gene Infomation:This gene encodes a member of the bone morphogeneticprotein (BMP) receptor family of transmembrane serine/threoninekinases. The ligands of this receptor are BMPs, which are membersof the TGF-beta superfamily. BMPs are involved in endochondral boneformation and embryogenesis. These proteins transduce their signalsthrough the formation of heteromeric complexes of 2 different typesof serine (threonine) kinase receptors: type I receptors of about50-55 kD and type II receptors of about 70-80 kD. Type II receptorsbind ligands in the absence of type I receptors, but they requiretheir respective type I receptors for signaling, whereas type Ireceptors require their respective type II receptors for ligandbinding. Mutations in this gene have been associated with primarypulmonary hypertension.
Antigen:This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the Central region of human BMPR1B.
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:RB31760
Dilution:WB::1:1000IHC::1:10~50
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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.