Anti-Bag1 Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:IgG1

Host:Mouse

Application:WB

Purify method:Affinity purified

Species:Transfected

Gene Name:bag1

Synonyms:HAP;BAG-1;RAP46.

Gene Synonyms:Bag 1;BAG family molecular chaperone regulator 1;BAG-1;BAG1;BAG1_HUMAN;BCL 2 Associated Athanogene 1;BCL 2 associated athanogene;BCL 2 binding athanogene 1;Bcl-2-associated athanogene 1;BCL2 associated athanogene 1;BCL2 associated athanogene;Glucocorticoi

Gene Full Name:

Gene Infomation:

Antigen:Purified recombinant human Bag1 protein fragments expressed in E.coli.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:Human

Reaction:Transfected

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:2C12-A8-1D7

Dilution:WB 1:1000

Mole Mass:52/46/33kDa

Location:Isoform 1: Nucleus. Cytoplasm.Note: Isoform 1 localizes predominantly to the nucleus.Isoform 2: Cytoplasm. Nucleus.Note: Isoform 2 localizes to the cytoplasm and shuttles into the nucleus in response to heat shock.

Concentration:7.5mg/ml

Sequence Similarity:Contains 1 BAG domain.Contains 1 ubiquitin-like domain.

Gene Id:573

SwissProt ID:Q99933

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Background:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.Inhibits the pro-apoptotic function of PPP1R15A,and has anti-apoptotic activity.Markedly increases the anti-cell death function of BCL2 induced by various stimuli.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.