Anti-Bcl-2 Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG2a

Host:Mouse

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:bcl2

Synonyms:Apoptosis regulator Bcl 2 ；Apoptosis regulator Bcl-2 ；Apoptosis regulator Bcl2 ；AW986256 ；B cell CLL/lymphoma 2 ；B cell leukemia/lymphoma 2 ；Bcl-2 ；Bcl2 ；BCL2_HUMAN ；C430015F12Rik ；D630044D05Rik ；D830018M01Rik ；Leukemia/lymphoma, B-cell, 2 ；Oncogene B-cell leukemia 2 ；PPP1R50 ；Protein phosphatase 1, regulatory subunit 50.

Gene Synonyms:Bcl-2; PPP1R50

Gene Full Name:

Gene Infomation:This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]

Antigen:Recombinant protein corresponding to fragment (aa/1-195) BCL2.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:

Mole Mass:29

Location:Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein

Concentration:1mg/ml

Sequence Similarity:Belongs to the Bcl-2 family.

Gene Id:596

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:This antibody detects endogenous levels of BCL2.

Storage:

Buffer condition:Each vial contains 100 μg IgG in 100 μl of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.