Anti-C3 Rabbit pAb
- 100ug (NP32394) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC
Purify method:Affinity purified
Species:Human,Mouse,Rat
Gene Name:C3
Synonyms:AHUS5;ARMD9;ASP;C3a;C3b;CPAMD1;HEL-S-62p
Gene Synonyms:C3
Gene Full Name:
Gene Infomation:
Antigen:Recombinant protein of human C3
Antigen Synonyms:AHUS5;ARMD9;ASP;C3a;C3b;CPAMD1;HEL-S-62p
Clonality:Polyclonal antibody
Source:Human
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB::1:500 - 1:2000IHC::1:50 - 1:100
Mole Mass:170kDa
Location:
Concentration:
Sequence Similarity:
Gene Id:718
SwissProt ID:
Unigene:
Nucleotide Accession:
Tissue specificity:
Storage:
Buffer condition:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:
Molar Function:Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.