Anti-C7 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:Rabbit IgG

Host:Rabbit

Application:ELISA,WB

Purify method:Affinity purified

Species:Mouse

Gene Name:C7

Synonyms:

Gene Synonyms:C7

Gene Full Name:

Gene Infomation:

Antigen:Fusion protein of human C7

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::500-2000

Mole Mass:94 kDa

Location:

Concentration:

Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

Nucleotide Accession:BC063851

Tissue specificity:

Storage:

Buffer condition:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Background:

Molar Function:The complement cascade is a multi-protein system that functions to clear pathogens from an infected host. Part of the innate (unchanging) immune system, the complement cascade consists of proteins and inactive zymogens that are present in blood and are stimulated by one of several triggers. Once stimulated, the cascade relays amplified responses throughout the body, ultimately activating the cell-killing membrane attack complex which can insert itself into the cell membrane and cause the cell to lyse. C7 (complement component 7) is an 843 amino acid secreted protein that participates in the formation of membrane attack complex (MAC), a complex that forms pores in the plasma membrane of target cells for innate and adaptive immune responses. As a membrane anchor, C7 exists as a monomer or dimer and can form multimeric rosettes with C5β. C7 defects are the cause of component C7 deficiency (C7D), characterized by recurrent bacterial infections caused by Neisseria meningitidis.

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.