Anti-CCNT1 (Center) Rabbit pAb
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Antibody type:Flowcytometry
Label:Unconjugated
Modification:
Isotype:Rabbit Ig
Host:Rabbit
Application:WB,FC
Purify method:Affinity purified
Species:Human,Mouse
Gene Name:ccnt1
Synonyms:Cyclin-T1, CycT1, Cyclin-T, CCNT1
Gene Synonyms:
Gene Full Name:
Gene Infomation:CCNT1 belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases. Different cyclinsexhibit distinct expression and degradation patterns whichcontribute to the temporal coordination of each mitotic event. Thiscyclin tightly associates with CDK9 kinase, and was found to be amajor subunit of the transcription elongation factor p-TEFb. Thekinase complex containing this cyclin and the elongation factor caninteract with, and act as a cofactor of human immunodeficiencyvirus type 1 (HIV-1) Tat protein, and was shown to be bothnecessary and sufficient for full activation of viraltranscription. This cyclin and its kinase partner were also foundto be involved in the phosphorylation and regulation of thecarboxy-terminal domain (CTD) of the largest RNA polymerase IIsubunit.
Antigen:This CCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids from the Central region of human CCNT1.
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:RB19562
Dilution:WB::1:1000FCM::1:10~50
Mole Mass:
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Gene Id:
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Unigene:
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Tissue specificity:
Storage:
Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.