Anti-CD3 zeta Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:Rabbit IgG

Host:Rabbit

Application:ICC/IF,FC

Purify method:Affinity Chromatography

Species:Human

Gene Name:

Synonyms:CD3-zeta; T-cell receptor T3 zeta chain; T3Z; TCRZ; CD247;

Gene Synonyms:

Gene Full Name:

Gene Infomation:Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

Antigen:A synthesized peptide derived from human CD3 zeta

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:

Reaction:CD3 zeta Antibody detects endogenous levels of total CD3 zeta

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:ICC/IF 1:100~1:200 FC 1:20

Mole Mass:kDa

Location:Cell membrane > Multi-pass membrane protein;

Concentration:

Sequence Similarity:Belongs to the G-protein coupled receptor 1 family.

Gene Id:

SwissProt ID:P20963

Unigene:

Nucleotide Accession:

Tissue specificity:CD3 zeta Antibody detects endogenous levels of total CD3 zeta

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Background:Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.