Anti-CEA(CD66e) Rabbit pAb
- 100ug (NP21006) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC,ICC/IF
Purify method:Affinity Chromatography
Species:Human
Gene Name:
Synonyms:adhesion molecule 5; CD66e; Ceacam5; Meconium antigen 100;
Gene Synonyms:
Gene Full Name:
Gene Infomation:Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity. Expression of CEA is correlated with tumerogenicity, and it has been shown to play a role in cell migration, adhesion and invasion in culture cells, as well as in metastasis in vivo.
Antigen:A synthesized peptide derived from human CEA(CD66e)
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:CEA(CD66e) Antibody detects endogenous levels of total CEA(CD66e)
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Mole Mass:180-220kDa
Location:Cell membrane > Lipid-anchor > GPI-anchor;
Concentration:
Sequence Similarity:Contains 7 Ig-like (immunoglobulin-like) domains.
Gene Id:
SwissProt ID:P06731
Unigene:
Nucleotide Accession:
Tissue specificity:CEA(CD66e) Antibody detects endogenous levels of total CEA(CD66e)
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Background:Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.