Anti-CHRNG (N-term) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:chrng

Synonyms:Acetylcholine receptor subunit gamma, CHRNG, ACHRG

Gene Synonyms:

Gene Full Name:

Gene Infomation:The mammalian muscle-type acetylcholine receptor is atransmembrane pentameric glycoprotein with two alpha subunits, onebeta, one delta, and one epsilon (in adult skeletal muscle) orgamma (in fetal and denervated muscle) subunit. This gene, whichencodes the gamma subunit, is expressed prior to the thirty-thirdweek of gestation in humans. The gamma subunit of the acetylcholinereceptor plays a role in neuromuscular organogenesis and ligandbinding and disruption of gamma subunit expression prevents thecorrect localization of the receptor in cell membranes. Mutationsin this gene cause Escobar syndrome and a lethal form of multiplepterygium syndrome. Muscle-type acetylcholine receptor is the majorantigen in the autoimmune disease myasthenia gravis.

Antigen:This CHRNG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human CHRNG.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB37063

Dilution:WB::1:1000

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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

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Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.