Anti-CaMKII-α Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:IgG1

Host:Mouse

Application:WB

Purify method:Affinity purified

Species:Human,Mouse

Gene Name:CAMK2A

Synonyms:CAMKA;CAMK2A.

Gene Synonyms:Alpha CaMKII ;Calcium calmodulin dependent protein kinase II ;Calcium/calmodulin dependent protein kinase II alpha B subunit ;Calcium/calmodulin dependent protein kinase type II alpha chain ;Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha ;Calcium/calmodulin-dependent protein kinase II alpha ;Calcium/calmodulin-dependent protein kinase II-alpha ;Calcium/calmodulin-dependent protein kinase type II subunit alpha ;Calcium/calmodulin-dependent protein kinase type IIA ;CaM kinase II alpha chain ;CaM kinase II alpha subunit ;CaM kinase II subunit alpha ;CaMK II alpha subunit ;CaMK-II subunit alpha ;Camk2a ;CAMKA ;CaMKII ;CaMKIINalpha ;EC 2.7.11.17 ;KCC2A_HUMAN ;KIAA0968 ;MGC123320 ;MGC139375 ;MGC155201 ;mKIAA0968 ;PK2CDD ;PKCCD ;R74975 ;zgc:112538 ;zgc:123320.

Gene Full Name:

Gene Infomation:

Antigen:Purified recombinant human CaMKII-α protein fragments expressed in E.coli.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:

Reaction:This antibody detects endogenous levels of CaMKII-α and does not cross-react with related proteins.

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:5D9-G10-G8

Dilution:WB 1:1000

Mole Mass:50kDa

Location:Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse. Postsynaptic lipid rafts.

Concentration:3.0mg/ml

Sequence Similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.Contains 1 protein kinase domain.

Gene Id:815

SwissProt ID:Q9UQM7

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.

Background:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.