Anti-Caspase-6 p18 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:Rabbit IgG

Host:Rabbit

Application:WB,IP

Purify method:Affinity Chromatography

Species:Human

Gene Name:

Synonyms:Apoptotic protease MCH2; CASP6; Caspase 6; Caspase 6 apoptosis related cysteine protease; Caspase-6 subunit p11; Caspase-6 subunit p20; Mch2

Gene Synonyms:

Gene Full Name:

Gene Infomation:Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.

Antigen:A synthesized peptide derived from human Caspase-6 p18

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:

Reaction:Caspase-6 p18 Antibody detects endogenous levels of Caspase-6 p18

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB 1:1000~1:2000 IP 1:50

Mole Mass:18,33kDa

Location:

Concentration:

Sequence Similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

Gene Id:

SwissProt ID:P55212

Unigene:

Nucleotide Accession:

Tissue specificity:Caspase-6 p18 Antibody detects endogenous levels of Caspase-6 p18

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Background:Caspase-6 is one of the major executioner caspases functioning in cellular apoptotic processes. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.