Anti-Cortactin Ascites Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgM

Host:Mouse

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:cortactin

Synonyms:Src substrate cortactin, Amplaxin, Oncogene EMS1, CTTN, EMS1

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene is overexpressed in breast cancer and squamouscell carcinomas of the head and neck. The encoded protein islocalized in the cytoplasm and in areas of the cell-substratumcontacts. This gene has two roles: (1) regulating the interactionsbetween components of adherens-type junctions and (2) organizingthe cytoskeleton and cell adhesion structures of epithelia andcarcinoma cells. During apoptosis, the encoded protein is degradedin a caspase-dependent manner. The aberrant regulation of this genecontributes to tumor cell invasion and metastasis. Three splicevariants that encode different isoforms have been identified forthis gene.

Antigen:Purified His-tagged Cortactin protein(Fragment) was used to produced this monoclonal antibody.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:401CT8.6.3

Dilution:WB::1:1000~8000

Mole Mass:

Location:

Concentration:

Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:

Buffer condition:Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.