Anti-Cyclin H Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:IgG2b

Host:Mouse

Application:WB,IP

Purify method:Affinity purified

Species:Human

Gene Name:ccnh

Synonyms:CAK; p34; p37

Gene Synonyms:6330408H09Rik;AI661354;AV102684;AW538719;CAK;CAK complex subunit;ccnh;CCNH_HUMAN;CDK activating kinase;CDK activating kinase complex subunit;Cyclin dependent kinase activating kinase;cyclin dependent kinase activating kinase complex subunit;Cyclin H; Cycl

Gene Full Name:

Gene Infomation:

Antigen:Purified recombinant human Cyclin H protein fragments expressed in E.coli.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:Human

Reaction:This antibody detects endogenous levels of Cyclin H and does not cross-react with related proteins.

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:4E11-G2-D7

Dilution:WB 1:1000

Mole Mass:38kDa

Location:Nucleus.

Concentration:

Sequence Similarity:Belongs to the cyclin family. Cyclin C subfamily.

Gene Id:902

SwissProt ID:P51946

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol

Background:Cyclin H belongs to a conserved cyclin family that plays a critical role in the regulation of cell cycle dependent kinases (CDKs) necessary for cell cycle progression. In general, the activity of CDKs requires the binding of appropriate cyclins as well as phosphorylation driven by Cdk-activating kinase (CAK). Involved in cell cycle control and in RNA transcription by RNA polymerase II.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.