Anti-DDR2 Ascites Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG1

Host:Mouse

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:ddr2

Synonyms:Discoidin domain-containing receptor 2, Discoidin domain receptor 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD167b, DDR2, NTRKR3, TKT, TYRO10

Gene Synonyms:

Gene Full Name:

Gene Infomation:Receptor tyrosine kinases (RTKs) play a key role in thecommunication of cells with their microenvironment. These moleculesare involved in the regulation of cell growth, differentiation, andmetabolism. In several cases the biochemical mechanism by whichRTKs transduce signals across the membrane has been shown to beligand induced receptor oligomerization and subsequentintracellular phosphorylation. This autophosphorylation leads tophosphorylation of cytosolic targets as well as association withother molecules, which are involved in pleiotropic effects ofsignal transduction. RTKs have a tripartite structure withextracellular, transmembrane, and cytoplasmic regions. This geneencodes a member of a novel subclass of RTKs and contains adistinct extracellular region encompassing a factor VIII-likedomain. Alternative splicing in the 5' UTR results in multipletranscript variants encoding the same protein. [provided byRefSeq].

Antigen:This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:484CT5.5.4

Dilution:WB::1:100~1600

Mole Mass:

Location:

Concentration:

Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:

Buffer condition:Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.