Anti-Dynactin 1(N-term) Mouse mAb

Antibody type:Loading control antibody

Label:Unconjugated

Modification:Unmodification

Isotype:IgG2b

Host:Mouse

Application:WB,IP

Purify method:Affinity purified

Species:Human

Gene Name:dctn1

Synonyms:P135; DP-150; DAP-150

Gene Synonyms:150 kDa dynein associated polypeptide;150 kDa dynein-associated polypeptide;DAP 150;DAP-150;DAP150;DCTN 1;DCTN1;DCTN1_HUMAN;DP 150;DP-150;DP150;Dynactin 1 (p150 Glued (Drosophila) homolog);dynactin 1 (p150 glued homolog Drosophila);Dynactin 1;Dynactin sub

Gene Full Name:

Gene Infomation:

Antigen:Purified recombinant Dynactin 1 protein fragments expressed in E.coli

Antigen Synonyms:

Clonality:Monclonal antibody

Source:Human

Reaction:This antibody detects endogenous levels of Dynactin 1(N-terminus),and does not cross-react with related proteins.

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:3D5-C6-D5

Dilution:WB 1:500

Mole Mass:150kDa

Location:Cytoplasm

Concentration:

Sequence Similarity:Belongs to the dynactin 150 kDa subunit family.Contains 1 CAP-Gly domain.

Gene Id:1639

SwissProt ID:Q14203

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Background:Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.