Anti-EIF4EBP1 Mouse mAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:Unknown
Host:Mouse
Application:WB
Purify method:Affinity purified
Species:Human
Gene Name:eif4ebp1
Synonyms:Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1
Gene Synonyms:
Gene Full Name:
Gene Infomation:This gene encodes one member of a family of translationrepressor proteins. The protein directly interacts with eukaryotictranslation initiation factor 4E (eIF4E), which is a limitingcomponent of the multisubunit complex that recruits 40S ribosomalsubunits to the 5' end of mRNAs. Interaction of this protein witheIF4E inhibits complex assembly and represses translation. Thisprotein is phosphorylated in response to various signals includingUV irradiation and insulin signaling, resulting in its dissociationfrom eIF4E and activation of mRNA translation. [provided byRefSeq].
Antigen:This EIF4EBP1 monoclonal antibody is generated from mouse immunized with EIF4EBP1 recombinant protein.
Antigen Synonyms:
Clonality:Monclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:319CT22.8.2
Dilution:WB::1:100~250
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Buffer condition:Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.