Anti-EWSR1 (C-term) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB,IF

Purify method:Affinity purified

Species:Human

Gene Name:ewsr1

Synonyms:RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene encodes a multifunctional protein that isinvolved in various cellular processes, including gene expression,cell signaling, and RNA processing and transport. The proteinincludes an N-terminal transcriptional activation domain and aC-terminal RNA-binding domain. Chromosomal translocations betweenthis gene and various genes encoding transcription factors resultin the production of chimeric proteins that are involved intumorigenesis. These chimeric proteins usually consist of theN-terminal transcriptional activation domain of this protein fusedto the C-terminal DNA-binding domain of the transcription factorprotein. Mutations in this gene, specifically a t(11;22)(q24;q12)translocation, are known to cause Ewing sarcoma as well asneuroectodermal and various other tumors. Alternative splicing ofthis gene results in multiple transcript variants. Relatedpseudogenes have been identified on chromosomes 1 and 14. [providedby RefSeq].

Antigen:This EWSR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-652 amino acids from the C-terminal region of human EWSR1.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB34553

Dilution:WB::1:1000ICC::1:10~50

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Storage:

Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

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Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.