Anti-ErbB4 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:Rabbit IgG

Host:Rabbit

Application:WB

Purify method:Affinity Chromatography

Species:Human,Mouse,Rat

Gene Name:

Synonyms:Avian erythroblastic leukemia viral oncogene homolog 4; E4ICD; ERBB4 intracellular domain; ERBB4; HER 4; HER4; Mer4;

Gene Synonyms:

Gene Full Name:

Gene Infomation:JunD, along with closely related family members c-Jun and JunB, is a transcription factor that can activate or repress a wide array of target genes. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N-terminal Kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinases. JunD activity can also be modulated by the MAPK pathway in response to growth factors.

Antigen:A synthesized peptide derived from human ErbB4

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:

Reaction:ErbB4 Antibody detects endogenous levels of ErbB4

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB 1:1000~1:2000

Mole Mass:185kDa

Location:Nucleus;

Concentration:

Sequence Similarity:Contains 1 bZIP (basic-leucine zipper) domain.

Gene Id:

SwissProt ID:Q15303

Unigene:

Nucleotide Accession:

Tissue specificity:ErbB4 Antibody detects endogenous levels of ErbB4

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Background:HER4/ErbB4, like other family members, has four ectodomains, a single transmembrane domain and a cytoplasmic tail containing the active tyrosine kinase domain. ErbB4 is ubiquitously expressed with the highest expression occurring in brain and heart. Involved in both normal tissue development and carcinogenesis.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.