Anti-FADD Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:IgG1

Host:Mouse

Application:WB,IP

Purify method:Affinity purified

Species:Human

Gene Name:FADD

Synonyms:GIG3;MORT1.

Gene Synonyms:FADD;FADD protein;FADD_HUMAN;Fas (TNFRSF6) associated via death domain;Fas associated via death domain;Fas associating death domain containing protein;Fas associating death domain containing protein;Fas associating protein;Fas associating protein with dea

Gene Full Name:

Gene Infomation:

Antigen:Recombinant human FADD protein.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:

Reaction:This antibody detects endogenous levels of FADD and does not cross-react with related proteins.

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:5E8-A7

Dilution:WB 1:500

Mole Mass:28kDa

Location:

Concentration:

Sequence Similarity:Contains 1 death domain.Contains 1 DED (death effector) domain.

Gene Id:8772

SwissProt ID:Q13158

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.

Background:Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.