Anti-FOLH1 (N-term) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB,IHC-P,IF

Purify method:Affinity purified

Species:Human

Gene Name:

Synonyms:Glutamate carboxypeptidase 2, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, FGCP, Glutamate carboxypeptidase II, GCPII, Membrane glutamate carboxypeptidase, mGCP, N-acetylated-alpha-linked acidic d

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene encodes a type II transmembrane glycoproteinbelonging to the M28 peptidase family. The protein acts as aglutamate carboxypeptidase on different alternative substrates,including the nutrient folate and the neuropeptideN-acetyl-l-aspartyl-l-glutamate and is expressed in a number oftissues such as prostate, central and peripheral nervous system andkidney. A mutation in this gene may be associated with impairedintestinal absorption of dietary folates, resulting in low bloodfolate levels and consequent hyperhomocysteinemia. Expression ofthis protein in the brain may be involved in a number ofpathological conditions associated with glutamate excitotoxicity.In the prostate the protein is up-regulated in cancerous cells andis used as an effective diagnostic and prognostic indicator ofprostate cancer. This gene likely arose from a duplication event ofa nearby chromosomal region. Alternative splicing gives rise tomultiple transcript variants encoding several different isoforms.

Antigen:This FOLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from the N-terminal region of human FOLH1.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::1:1000ICC::1:10~50IHC::1:10~50

Mole Mass:

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Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

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Tissue specificity:

Storage:

Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.