Anti-FOXO3A(Phospho-Ser253) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG

Host:Rabbit

Application:WB,IHC

Purify method:Affinity purified

Species:Human,Mouse,Rat

Gene Name:foxo3

Synonyms:AF6q21;AF6q21 protein;DKFZp781A0677;FKHR2;FKHRL 1;FKHRL1;FKHRL1P2;Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1;Forkhead box O3;Forkhead box O3A;Forkhead box protein O3;Forkhead box protein O3A;Forkhead Drosophila homolog of in rhabdomyosarcoma like 1;Forkhead homolog (rhabdomyosarcoma) like 1;Forkhead in rhabdomyosarcoma like 1;Forkhead in rhabdomyosarcoma-like 1;FOX O3A;FOXO2;foxo3;FOXO3_HUMAN;FOXO3A;MGC12739;MGC31925.

Gene Synonyms:FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2

Gene Full Name:

Gene Infomation:This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Antigen:The antiserum was produced against synthesized phosphopeptide derived from human FOXO3A around the phosphorylation site of serine 253 (A-V-SP-M-D).

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:

Mole Mass:71

Location:Cytoplasm › cytosol. Nucleus. Note: Translocates to the nucleus upon oxidative stress and in the absence of survival factors.

Concentration:

Sequence Similarity:Contains 1 fork-head DNA-binding domain.

Gene Id:2309

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:This antibody detects endogenous levels of FOXO3A and does not cross-react with related proteins.

Storage:

Buffer condition:10mM PBS with 0.02% sodium azide, 50% glycerol.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.