Anti-Fas Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:IgG2b

Host:Mouse

Application:WB

Purify method:Affinity purified

Species:Human,Rat

Gene Name:Fas

Synonyms:APT1;CD95;FAS1;APO-1;FASTM;ALPS1A;TNFRSF6;FAS

Gene Synonyms:ALPS 1A;ALPS1A;APO 1;Apo 1 antigen;APO 1 cell surface antigen;Apo-1 antigen;APO1;Apo1 antigen;APO1 cell surface antigen;Apoptosis antigen 1;Apoptosis mediating surface antigen FAS;Apoptosis-mediating surface antigen FAS;APT 1;APT1;CD 95;CD 95 antigen;CD95

Gene Full Name:

Gene Infomation:

Antigen:Purified recombinant human Fas protein expressed in E.coli.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:

Reaction:This antibody detects endogenous levels ofFas and does not cross-react with related proteins.

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:8C1-B9-F12

Dilution:WB 1:1000

Mole Mass:45kDa

Location:Cell membrane; Single-pass type I membrane protein.

Concentration:

Sequence Similarity:Contains 1 death domain._x000D_Contains 3 TNFR-Cys repeats.

Gene Id:355

SwissProt ID:P25445

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.

Background:Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.