Anti-HAVCR2 (Center) Rabbit pAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:Rabbit Ig
Host:Rabbit
Application:WB
Purify method:Affinity purified
Species:Human
Gene Name:
Synonyms:Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3, HAVCR2, TIM3, TIMD3
Gene Synonyms:
Gene Full Name:
Gene Infomation:CD4 (MIM 186940)-positive T helper lymphocytes can bedivided into types 1 (Th1) and 2 (Th2) on the basis of theircytokine secretion patterns. Th1 cells and their associatedcytokines are involved in cell-mediated immunity to intracellularpathogens and delayed-type hypersensitivity reactions, whereas Th2cells are involved in the control of extracellular helminthicinfections and the promotion of atopic and allergic diseases. The 2types of cells also cross-regulate the functions of the other. TIM3is a Th1-specific cell surface protein that regulates macrophageactivation and enhances the severity of experimental autoimmuneencephalomyelitis in mice.
Antigen:This HAVCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2.
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB::1:2000
Mole Mass:
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Gene Id:
SwissProt ID:
Unigene:
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Tissue specificity:
Storage:
Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.