Anti-HDAC1(Phospho-Ser421/423) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG

Host:Rabbit

Application:WB,IHC

Purify method:Affinity purified

Species:Human,Mouse,Rat

Gene Name:hdac1

Synonyms:DKFZp686H12203;GON 10;HD 1;HD1;HDAC 1;HDAC1;hdac1: histone deacetylase 1;HDAC1_HUMAN;Histone deacetylase 1 (HD1);Histone deacetylase 1;Reduced potassium dependency yeast homolog like 1;RPD3 (reduced potassium dependency yeast homolog) like 1;RPD3 (reduced potassium dependency);RPD3;RPD3L1.

Gene Synonyms:HD1; RPD3; GON-10; RPD3L1

Gene Full Name:

Gene Infomation:Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]

Antigen:The antiserum was produced against synthesized phosphopeptide derived from human HDAC1 around the phosphorylation site of serine 421/423 (E-F-SP-D- SP –E-E).

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:

Mole Mass:55

Location:Nucleus.

Concentration:

Sequence Similarity:Belongs to the histone deacetylase family. HD type 1 subfamily.

Gene Id:3065

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:This antibody detects endogenous levels of HDAC1 and does not cross-react with related proteins.

Storage:

Buffer condition:10mM PBS with 0.02% sodium azide, 50% glycerol.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.