Anti-HDAC4(N-term) Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:IgG2a

Host:Mouse

Application:WB,IP

Purify method:Affinity purified

Species:Human,Mouse,Rat,Monkey

Gene Name:hdac4

Synonyms:HD4;AHO3;BDMR;HDACA;HA6116;HDAC-4;HDAC-A

Gene Synonyms:EC 3.5.1.98;HA6116;HD 4;HD4;HDAC 4;HDAC A;HDAC4;HDAC4_HUMAN;HDACA;Histone Deacetylase 4; Histone Deacetylase A;KIAA0288.

Gene Full Name:

Gene Infomation:

Antigen:Purified recombinant human HDAC4 protein fragments expressed in E.coli

Antigen Synonyms:

Clonality:Monclonal antibody

Source:Human

Reaction:This antibody detects endogenous levels of HDAC4 and does not cross-react with related proteins

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:4A3-H7-C6

Dilution:WB 1:1000

Mole Mass:140kDa

Location:Nucleus. Cytoplasm

Concentration:

Sequence Similarity:Belongs to the histone deacetylase family. HD type 2 subfamily

Gene Id:9759

SwissProt ID:P56524

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol

Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.