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Anti-HK2(Hexokinase II) (Center) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB,IHC-P

Purify method:Affinity purified

Species:Human

Gene Name:hk2

Synonyms:Hexokinase-2, Hexokinase type II, HK II, Muscle form hexokinase, HK2

Gene Synonyms:

Gene Full Name:

Gene Infomation:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV.Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P.Hexokinase activity is involved in the first step in several metabolic pathways.HK3 is bound to the outer mitochondrial membrane.Its hydrophobic N-terminal sequence may be involved in membrane bindng.It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle.The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other.The catalytic activity is associated with the C-terminus while regulatory function is associated wiht the N-terminus.Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.

Antigen:This HK2 (Hexokinase II) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-483 amino acids from the Central region of human HK2 (Hexokinase II).

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

  • Western blot (1:100 to 1:500)
  • Immunofluorescence (1:50 to 1:400)
  • Immunohistochemistry (1:200 to 1:500)
  • Flow cytometry analysis (1:200 to 1:500)
  • Enzyme-linked Immunosorbent Assay (1:100-1:5000)
NoteUsers are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB5333

Dilution:WB::1:1000IHC::1:100

Mole Mass:

Location:

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Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

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Tissue specificity:

Storage:

Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.