Anti-Hsp70Rabbit pAb
- 100ug (NP21522) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC,ICC/IF,FC
Purify method:Affinity Chromatography
Species:Human,Mouse,Rat
Gene Name:
Synonyms:HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HSPA1A;
Gene Synonyms:
Gene Full Name:
Gene Infomation:p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.
Antigen:A synthesized peptide derived from human Hsp70
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:Hsp70 Antibodydetects endogenous levels of total Hsp70
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:100 FC 1:100
Mole Mass:70kDa
Location:Cytoplasm;
Concentration:
Sequence Similarity:Belongs to the p53 family.
Gene Id:
SwissProt ID:P0DMV8
Unigene:
Nucleotide Accession:
Tissue specificity:Hsp70 Antibodydetects endogenous levels of total Hsp70
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Background:In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.