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Anti‐Human IL‐17A

Antibody type:Flowcytometry

Label:Unconjugated

Modification:Unmodification

Isotype:IgG1

Host:Mouse

Application:FCM,WB

Purify method:

Species:Human

Gene Name:

Synonyms:

Gene Synonyms:

Gene Full Name:

Gene Infomation:

Antigen:

Antigen Synonyms:

Clonality:

Source:

Reaction:

Form:Liquid

Tested Applications:

  • Western blot (1:100 to 1:500)
  • Immunofluorescence (1:50 to 1:400)
  • Immunohistochemistry (1:200 to 1:500)
  • Flow cytometry analysis (1:200 to 1:500)
  • Enzyme-linked Immunosorbent Assay (1:100-1:5000)
NoteUsers are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:3B9-F2

Dilution:

Mole Mass:

Location:

Concentration:

Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:4℃保存,避免反复冻融

Buffer condition:含0.09%(w/v) NaN3

Background:

Molar Function:3B9-F2抗体与人的Il-17A反应,3B9-F2抗体是中和抗体。IL‐17A是 CD4+ T 相关细胞因子,在细胞系中促进炎症反应。在类风湿关节炎,哮喘,多发性硬化,牛皮癣,移植排斥中提升。高水平的 IL‐17A同源二聚体通过激活外周血CD4+ T细胞产生。 在人的纤维母细胞中IL‐17A 提高ICAM‐1) 表达。人IL‐17A 也刺激上皮或成纤维细胞分泌IL‐6, IL‐8, G‐CSF, and PGE2. 在 IL‐17A存在时, 纤维母细胞维持CD34+ 造血干细胞增值和诱导成中性粒细胞。

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.