Anti-IGF1R(Phospho-Tyr980) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG

Host:Rabbit

Application:WB,IHC

Purify method:Affinity purified

Species:Human,Mouse,Rat

Gene Name:igf1r

Synonyms:CD221;CD221;CD221 antigen;IGF 1 receptor;IGF 1R;IGF 1R;IGF I receptor;IGF-I receptor;IGF1R;IGF1R;IGF1R_HUMAN;IGFIR;IGFIRC;IGFIRC;IGFR;Insulin like growth factor 1 receptor;Insulin like growth factor 1 receptor;Insulin like growth factor 1 receptor precursor;Insulin like growth factor 1 receptor precursor;Insulin-like growth factor 1 receptor beta chain;Insulin-like growth factor I receptor;JTK13;JTK13;MGC142170;MGC142172;MGC18216.

Gene Synonyms:IGFR; CD221; IGFIR; JTK13

Gene Full Name:

Gene Infomation:This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]

Antigen:The antiserum was produced against synthesized phosphopeptide derived from human IGF1R around the phosphorylation site of tyrosine 980 (P-E-YP-F-S ).

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:

Mole Mass:155

Location:Membrane; Single-pass type I membrane protein.

Concentration:

Sequence Similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.Contains 4 fibronectin type-III domains.Contains 1 protein kinase domain.

Gene Id:3480

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:This antibody detects endogenous levels of IGF1 Receptor protein.

Storage:

Buffer condition:10mM PBS with 0.02% sodium azide, 50% glycerol.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.