Anti-KLKB1 (C-term) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:klkb1

Synonyms:Plasma kallikrein, Fletcher factor, Kininogenin, Plasma prekallikrein, Plasma kallikrein heavy chain, Plasma kallikrein light chain, KLKB1, KLK3

Gene Synonyms:

Gene Full Name:

Gene Infomation:Plasma prekallikrein is a glycoprotein that participatesin the surface-dependent activation of blood coagulation,fibrinolysis, kinin generation and inflammation.It is synthesizedin the liver and secreted into the blood as a single polypeptidechain.Plasma prekallikrein is converted to plasma kallikrein byfactor XIIa by the cleavage of an internal Arg-Ile bond.Plasmakallikrein therefore is composed of a heavy chain and a light chainheld together by a disulphide bond.The heavy chain originatesfrom the amino-terminal end of the zymogen and contains 4 tandemrepeats of 90 or 91 amino acids.Each repeat harbors a novelstructure called the apple domain.The heavy chain is required forthe surface-dependent pro-coagulant activity of plasma kallikrein.The light chain contains the active site or catalytic domain of theenzyme and is homologous to the trypsin family of serine proteases.Plasma prekallikrein deficiency causes a prolonged activatedpartial thromboplastin time in patients.

Antigen:This KLKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-537 amino acids from the C-terminal region of human KLKB1.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB34055

Dilution:WB::1:1000

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Gene Id:

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Unigene:

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Storage:

Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.