Anti-Keratin 18 Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:IgG2a

Host:Mouse

Application:WB,ICC

Purify method:Affinity purified

Species:Human,Monkey

Gene Name:krt18

Synonyms:K18;CYK18.

Gene Synonyms:Cell proliferation inducing gene 46 protein;Cell proliferation inducing protein 46;Cell proliferation-inducing gene 46 protein;CK 18;CK-18;CK18;Cytokeratin 18;Cytokeratin endo B;Cytokeratin-18;Cytokeratin18;K 18;K18;K1C18_HUMAN;Keratin 18;Keratin D;Kerati

Gene Full Name:

Gene Infomation:

Antigen:Purified recombinant human Keratin 18 protein fragments expressed in E.coli.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:Human

Reaction:This antibody detects endogenous levels of Keratin 18 and does not cross-react with related proteins.

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:2B5-B6-F7

Dilution:WB 1:2000,ICC 1:800

Mole Mass:46kDa

Location:Cytoplasm ? perinuclear region

Concentration:

Sequence Similarity:Belongs to the intermediate filament family. Belongs to the intermediate filament family. Belongs to the intermediate filament family. Belongs to the intermediate filament family.

Gene Id:3875

SwissProt ID:P05783

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide 0.1mg/mlBSA and 50% glycerol.

Background:Involved in the uptake of thrombin-antithrombin complexes by hepatic cells By similarity. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.