Anti-LDB3 (Center) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:ldb3

Synonyms:LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein, LDB3 (HGNC:15710)

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene encodes a PDZ domain-containing protein. PDZmotifs are modular protein-protein interaction domains consistingof 80-120 amino acid residues. PDZ domain-containing proteinsinteract with each other in cytoskeletal assembly or with otherproteins involved in targeting and clustering of membrane proteins.The protein encoded by this gene interacts with alpha-actinin-2through its N-terminal PDZ domain and with protein kinase C via itsC-terminal LIM domains. The LIM domain is a cysteine-rich motifdefined by 50-60 amino acids containing two zinc-binding modules.This protein also interacts with all three members of the myozeninfamily. Mutations in this gene have been associated withmyofibrillar myopathy and dilated cardiomyopathy. Alternativelyspliced transcript variants encoding different isoforms have beenidentified; all isoforms have N-terminal PDZ domains while onlylonger isoforms (1, 2 and 5) have C-terminal LIM domains. [providedby RefSeq].

Antigen:This LDB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-262 amino acids from the Central region of human LDB3.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB36787

Dilution:WB::1:1000

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Sequence Similarity:

Gene Id:

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Unigene:

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Tissue specificity:

Storage:

Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.