Anti-LIMK1 (Phospho-Thr508) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:DB

Purify method:Affinity purified

Species:Human

Gene Name:limk1

Synonyms:LIM domain kinase 1, LIMK-1, LIMK1, LIMK

Gene Synonyms:

Gene Full Name:

Gene Infomation:There are approximately 40 known eukaryotic LIM proteins,so named for the LIM domains they contain. LIM domains are highlyconserved cysteine-rich structures containing 2 zinc fingers.Although zinc fingers usually function by binding to DNA or RNA,the LIM motif probably mediates protein-protein interactions. LIMkinase-1 and LIM kinase-2 belong to a small subfamily with a uniquecombination of 2 N-terminal LIM motifs and a C-terminal proteinkinase domain. LIMK1 is likely to be a component of anintracellular signaling pathway and may be involved in braindevelopment. LIMK1 hemizygosity is implicated in the impairedvisuospatial constructive cognition of Williams syndrome. [providedby RefSeq].

Antigen:This LIMK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Thr508 of human LIMK1.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB28259

Dilution:Other::DB:1:500

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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.

Background:

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Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.