Anti-LMNA (Center) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:lmna

Synonyms:Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1

Gene Synonyms:

Gene Full Name:

Gene Infomation:The nuclear lamina consists of a two-dimensional matrix ofproteins located next to the inner nuclear membrane. The laminfamily of proteins make up the matrix and are highly conserved inevolution. During mitosis, the lamina matrix is reversiblydisassembled as the lamin proteins are phosphorylated. Laminproteins are thought to be involved in nuclear stability, chromatinstructure and gene expression. Vertebrate lamins consist of twotypes, A and B. Through alternate splicing, this gene encodes threetype A lamin isoforms. Mutations in this gene lead to severaldiseases: Emery-Dreifuss muscular dystrophy, familial partiallipodystrophy, limb girdle muscular dystrophy, dilatedcardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilfordprogeria syndrome.

Antigen:This LMNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-427 amino acids from the Central region of human LMNA.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB21443

Dilution:WB::1:1000

Mole Mass:

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Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

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Tissue specificity:

Storage:

Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.