Anti-MEK5 Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG1

Host:Mouse

Application:WB

Purify method:Unpurification

Species:Human,Rat

Gene Name:MAP2K5

Synonyms:Dual specificity mitogen activated protein kinase kinase 5 ;Dual specificity mitogen-activated protein kinase kinase 5 ;EC 2.7.12.2 ;HsT17454 ;MAP kinase kinase 5 ;MAP kinase kinase MEK5b ;MAP2K5 ;MAPK/ERK kinase 5 ;MAPKK 5 ;MAPKK5 ;MEK 5 ;mitogen-activated protein kinase kinase 5 ;MKK5 ;MP2K5_HUMAN ;PRKMK5 ;Protein kinase, mitogen-activated, kinase 5 ;SAPKK5 ;SKK5.

Gene Synonyms:MEK5; MAPKK5; PRKMK5; HsT17454

Gene Full Name:

Gene Infomation:The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Antigen:Purified recombinant fragment of human MAP2K5 (AA: 63-180) expressed in E. Coli.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:1F9-F3-B6

Dilution:

Mole Mass:50kDa

Location:

Concentration:

Sequence Similarity:Contains 1 protein kinase domain.

Gene Id:5607

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:

Buffer condition:Purified antibody in PBS with 0.05% sodium azide.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.