Anti-MUC16 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:Rabbit IgG

Host:Rabbit

Application:WB,ICC/IF,FC

Purify method:Affinity Chromatography

Species:Human

Gene Name:

Synonyms:Cancer antigen 125; CA125; CA125 ovarian cancer; MUC 16; Mucin16; Ovarian cancer related tumor marker CA125;

Gene Synonyms:

Gene Full Name:

Gene Infomation:Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5-GTGACGT[AG][AG]-3), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.

Antigen:A synthesized peptide derived from human MUC16

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:

Reaction:MUC16 Antibody detects endogenous levels of MUC16

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB 1:5000~1:20000 ICC/IF 1:50~1:200 FC 1:100

Mole Mass:2353 kDa

Location:

Concentration:

Sequence Similarity:

Gene Id:

SwissProt ID:Q8WXI7

Unigene:

Nucleotide Accession:

Tissue specificity:MUC16 Antibody detects endogenous levels of MUC16

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Background:The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.