Anti-NFkB-p65(Phospho-Ser536) Rabbit pAb
- 100ug (NP13652) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:IgG
Host:Rabbit
Application:WB,IHC
Purify method:Affinity purified
Species:Human,Mouse,Rat
Gene Name:rela
Synonyms:Avian reticuloendotheliosis viral (v rel) oncogene homolog A;MGC131774;NF kappa B p65delta3;NFKB 3;NFKB3;Nuclear Factor NF Kappa B p65 Subunit;Nuclear factor NF-kappa-B p65 subunit;Nuclear factor of kappa light polypeptide gene enhancer in B cells 3;Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3;OTTHUMP00000233473;OTTHUMP00000233474;OTTHUMP00000233475;OTTHUMP00000233476;OTTHUMP00000233900;p65;p65 NF kappaB;p65 NFkB;RELA;TF65_HUMAN;Transcription Factor p65;v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65));V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A;v rel reticuloendotheliosis viral oncogene homolog A (avian);V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65;v-rel reticuloendotheliosis viral oncogene homolog A.
Gene Synonyms:p65; NFKB3
Gene Full Name:
Gene Infomation:NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Antigen:The antiserum was produced against synthesized phosphopeptide derived from human NFkB-p65 around the phosphorylation site of serine 536 (F-S-SP-I-A).
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:Human
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:
Mole Mass:69
Location:Nucleus. Cytoplasm. Note: Colocalized with DDX1 in the nucleus upon TNF-alpha induction By similarity. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B). Colocalizes with GFI1 in the nucleus after LPS stimu
Concentration:
Sequence Similarity:Contains 1 RHD (Rel-like) domain.
Gene Id:5970
SwissProt ID:
Unigene:
Nucleotide Accession:
Tissue specificity:This antibody detects endogenous levels of NF-Kb p65 and does not cross-react with related proteins.
Storage:
Buffer condition:10mM PBS with 0.02% sodium azide, 50% glycerol.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.