Anti-NMDAR1(Phospho-Ser897) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG

Host:Rabbit

Application:WB,IHC

Purify method:Affinity purified

Species:Human,Mouse,Rat

Gene Name:grin1

Synonyms:GluN1;Glutamate [NMDA] receptor subunit zeta 1;Glutamate [NMDA] receptor subunit zeta-1;Glutamate receptor ionotropic N methyl D aspartate 1;Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1;glutamate receptor ionotropic, NMDA 1;Grin 1;Grin1;MRD8;N methyl D aspartate receptor;N methyl D aspartate receptor channel;N methyl D aspartate receptor channel subunit zeta 1;N methyl D aspartate receptor subunit NR1;N-methyl-D-aspartate receptor;N-methyl-D-aspartate receptor subunit NR1;NMD-R1;NMDA 1;NMDA NR1;NMDA R1;NMDA receptor 1;NMDA1;NMDAR 1;NMDAR;Nmdar1;NMDZ1_HUMAN;NR 1;NR1.

Gene Synonyms:NR1; MRD8; GluN1; NMDA1; NMDAR1

Gene Full Name:

Gene Infomation:The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Antigen:The antiserum was produced against synthesized phosphopeptide derived from human NMDAR1 around the phosphorylation site of serine 897 (R-S-SP-K-D).

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:

Mole Mass:105

Location:Cell membrane; Multi-pass membrane protein. Cell junction › synapse › postsynaptic cell membrane. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density. Note: Enriched in postsynaptic plasma membrane and postsynaptic densities.

Concentration:

Sequence Similarity:Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily. [View classification]

Gene Id:2902

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:This antibody detects endogenous levels of NMDAR1 protein.

Storage:

Buffer condition:10mM PBS with 0.02% sodium azide, 50% glycerol.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.