Anti-NTNG2 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:Rabbit IgG

Host:Rabbit

Application:ELISA,WB

Purify method:Affinity purified

Species:Human

Gene Name:NTNG2

Synonyms:Lmnt2; NTNG1; LHLL9381; bA479K20.1

Gene Synonyms:NTNG2

Gene Full Name:

Gene Infomation:

Antigen:Synthetic peptide of human NTNG2

Antigen Synonyms:Lmnt2; NTNG1; LHLL9381; bA479K20.1

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::200-1000

Mole Mass:60 kDa

Location:

Concentration:

Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

Nucleotide Accession:NP_115925

Tissue specificity:

Storage:

Buffer condition:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Background:

Molar Function:Netrin G1 and Netrin G2, also referred to as laminet-1 and laminet-2, are membrane bound axon guidance molecules involved in synaptic formation and maintenance. They comprise a subgroup within the UNC-6/netrin family. Both genes have been associated with schizophrenia involving single nucleotide polymorphisms. They are both expressed in the brain but G1 is most predominantly expressed in the thalamus and G2 is most predominantly expressed in the cortex and hippocampus. These two proteins differ from classical netrins by their failure to bind netrin receptors, the presence of a glycosyl phosphatidylinositol membrane anchor, and the generation of multiple isoforms. Netrin G2 contains one laminin N-terminal domain and three laminin EGF-like domains. It selectively interacts with LRRC4 and this association may mediate cell adhesion. In addition, Netrin G2 is significantly downregulated in bladder transitional cell carcinoma (TCC) and may be a putative tumor suppressor gene.

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.