Anti-Nephrin (Phospho-Tyr119) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:DB

Purify method:Affinity purified

Species:Human

Gene Name:nephrin

Synonyms:Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene encodes a member of the immunoglobulin family ofcell adhesion molecules that functions in the glomerular filtrationbarrier in the kidney. The gene is primarily expressed in renaltissues, and the protein is a type-1 transmembrane protein found atthe slit diaphragm of glomerular podocytes. The slit diaphragm isthought to function as an ultrafilter to exclude albumin and otherplasma macromolecules in the formation of urine. Mutations in thisgene result in Finnish-type congenital nephrosis 1, characterizedby severe proteinuria and loss of the slit diaphragm and footprocesses.

Antigen:This Nephrin Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1193 of human Nephrin.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB28261

Dilution:Other::DB:1:500

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Unigene:

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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.

Background:

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Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.