Anti-PAX8 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:Rabbit IgG

Host:Rabbit

Application:IHC,ICC/IF

Purify method:Affinity Chromatography

Species:Human

Gene Name:

Synonyms:Paired box 8; Paired box gene 8; paired box homeotic gene 8; Paired box protein Pax 8; Paired domain gene 8; PAX 8;

Gene Synonyms:

Gene Full Name:

Gene Infomation:LAMP1 and LAMP2 (lysosome-associated membrane protein 1 and 2) are two abundant lysosomal membrane proteins. Both are transmembrane proteins and heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis. The carboxy terminus of LAMP1 is exposed to the cytoplam and contains a tyrosine sorting motif which targets LAMP to lysosomal membranes. LAMP1 and LAMP2 are 37% homologous in their protein sequences. The cellular functions of these two proteins are also overlap - both are involved in regulating lysosomal motility during lysosome-phagosome fusion and cholesterol trafficking.

Antigen:A synthesized peptide derived from human PAX8

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:

Reaction:PAX8 Antibody detects endogenous levels of PAX8

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:IHC 1:50~1:200 ICC/IF 1:50~1:200

Mole Mass:48 kDa

Location:Late endosome;

Concentration:

Sequence Similarity:Belongs to the LAMP family.

Gene Id:

SwissProt ID:Q06710

Unigene:

Nucleotide Accession:

Tissue specificity:PAX8 Antibody detects endogenous levels of PAX8

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Background:Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.