Anti-PDGFRα Mouse(7A3) Mouse mAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:IgG
Host:Mouse
Application:IHC
Purify method:Affinity Chromatography
Species:Human,Mouse,Rat
Gene Name:PDGFRA
Synonyms:PDGFRA
Gene Synonyms:CD140A; PDGFR2; PDGFR-2
Gene Full Name:
Gene Infomation:This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Antigen:Synthetic Peptide of PDGFRα at AA range of 1010-1090
Antigen Synonyms:
Clonality:Monclonal antibody
Source:
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:IHC::1:100-200
Mole Mass:180
Location:Cell membrane > Single-pass type I membrane protein;
Concentration:
Sequence Similarity:Contains 1 protein kinase domain.
Gene Id:5156
SwissProt ID:
Unigene:
Nucleotide Accession:
Tissue specificity:PDGFRα protein detects endogenous levels of PDGFRA
Storage:
Buffer condition:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.